Mass Spec and Proteomics > Instruments

List of Instrumentation for the CCIC MS&P Lab

Feel free to ask our staff members to show you the lab during your next visit.

Bruker 15 Tesla FT-ICR mass spectrometer
Ultrahigh resolution (>1,000,000) and mass accuracy (< 1 ppm). Equipped with a dual ionization source (MALDI and ESI). ETD and ECD options available. Used mostly for untargeted metabolomics, small molecule MALDI imaging, and top down proteomics.

Thermo Orbitrap Fusion HPLC-MS/MS System
Ultrahigh resolution and excellent mass accuracy. Used mostly for bottom-up proteomics.

Thermo Quantiva Triple Quadrupole HPLC MS/MS System
Ultrahigh sensitivity, used mostly for quantitative (targeted) metabolomics

Bruker amaZon ETD
Ultra performance, high sensitive proteomics ion trap with dual funnel ion guide and advanced ETD / PTR capabilities (Electron Transfer Dissociation and Proton Transfer Reaction) with a Dionex U3000 RSLC system.

Bruker maXis Electrospray
Ionization Quadrupole Time-of-Flight Mass Spectrometer for Ultra-High- Resolution Exact Mass and True Isotopic Measurements in both, MS and MS/MS mode with a Dionex U3000 RSLC system.

Bruker ultrafleXtreme MALDI-TOF-TOF MS with Proteineer fc II for LC-MALDI and ImagePrep
The Bruker-Daltonics UltrafleXtreme MALDI-TOF-TOF MS-Tissue Imaging Platform with collision- induced dissociation (CID) capabilities for structural determination by MALDI

Thermo Scientific LTQ Orbitrap
A LTQ Orbitrap XL exclusively used for advanced proteomic projects that require high resolution and high mass accuracy. This instrument is a unique hybrid mass spectrometer that combines a linear ion trap and an orbitrap mass analyzer. The system come equipped with a microspray ionization source from Michrome Bioresources and comprehensive U3000 Cap-LC system from Dionex .

Thermo Scientific Linear Quadrupole Ion Trap MS
The LTQ provides, ultra-fast cycle time, high sensitivity and tandem mass spectrometric analysis with many stages of CID MS analysis of liquid samples introduced by Capillary-LC (from Dionex – a LC Packings Company) or infusion for high throughput proteomics. Samples can be run faster and still deliver higher quality data, allowing identification and quantification of low-level analytes in complex matrices.

Thermo Scientific DSQ-II GC-MS
Low-resolution + EI auto-injector, split/splitless injections and flow control.

Waters Xevo TQ-S triple quadruople
For targeting quantitation of proteins and small molecules complete with nano-Acquity 2D-UPLC and Trizac source.

GE Pharmacia AKTA FPLC Purifier 10
For rapid purification of proteins at low to medium pressures with high performance purification and characterization. AKTA is a high end liquid chromatography system designed for fast and reliable separations of peptides and nucleic acids from g to mg scale at flow rates 0.001 ml/min to 10 ml/min and pressures up to 25 Mpa.

Ettan Spot Handling Workstation
The Ettan Spot Handling Workstation and Typhoon is a fully integrated instrument for automatic processing visualization and transfer of proteins from polyacrylamide electrophoresis gels for direct mass spectral analyses.